fig2

Figure 2. (A) Schematic of super-assembly fabrication processes of a fully biodegradable micro-ZISC, including screen printing, electrochemical sintering, electrochemical deposition, and device assembly. (B) Photograph of micro-ZISC. (C) XRD patterns of Zn and Zn@ppy. (D) Optical images of silk-encapsulated micro-ZISC before implantation. (E-I) In-vivo degradation evaluation of micro-ZISC device after being implanted in the subcutaneous region of rats. (J) Cell viability of plasticized silk films, NaCl/agarose gel, silk protein-Zn and silk protein-Zn@ppy films. (K) Fluorescent images showing cell viability, with green (calcein-AM) and red [propidium iodide (PI)] representing live and dead RAW264.7 cells, respectively^[103]. Reproduced with permission from Ref.^[103] (Copyright 2021, American Chemical Society).